Publications

Lawrence Impey's selected original research papers

Asfaw D, Jordanov I, Impey L, Namburete A, Lee R, Georgieva A.
Multimodal Deep Learning for Predicting Adverse Birth Outcomes Based on Early Labour Data.
Bioengineering (Basel). 2023 Jun 19;10(6):730.

Aderoba AK, Ioannou C, Kurinczuk JJ, Quigley MA, Cavallaro A, Impey L; Oxford Growth Restriction Identification Programme (OxGRIP) Group.
The impact of a universal late third-trimester scan for fetal growth restriction on perinatal outcomes in term singleton births: A prospective cohort study.
BJOG. 2023 Jun;130(7):791-802. doi:

Impey L.
Middle cerebral artery Doppler improves risk stratification of small for gestational age babies at a peri-viable gestation.
BJOG. 2023 Apr;130(5):494.

Impey L, Abadia-Cuchi N.
Reduced fetal movements: Time to move on?
BJOG. 2023 May;130(6):546-548.

Mathewlynn S, Beriwal S, Ioannou C, Cavallaro A, Impey L.
Abnormal umbilical artery pulsatility index in appropriately grown fetuses in the early third trimester: an observational cohort study.
J Matern Fetal Neonatal Med. 2023 Dec;36(1):2152670.

Horton-Bell M, Hamilton S, Keelagher R, Allen S, De Burca A, Ioannou C, Impey L, Cilliers D.
Prenatal diagnosis of PERCHING syndrome caused by homozygous loss of function variant in the KLHL7 gene.
Prenat Diagn. 2022 Nov;42(12):1481-1483.

Hedditch A, Laudat M, Ellaway P, Impey L.
Do specific maternal sensations experienced in late pregnancy correlate to a breech presenting baby? Evaluation of a simple maternal questionnaire.
Birth. 2023 Sep;50(3):565-570.

Garbagnati M, Aye CYL, Cavallaro A, Mathewlynn S, Ioannou C, Impey L.
Ultrasound predictors of adverse outcome in pregnancy complicated by pre-existing and gestational diabetes.
Acta Obstet Gynecol Scand. 2022 Jul;101(7):787-793.

Aderoba AK, Nasir N, Quigley M, Impey L, Rivero-Arias O, Kurinczuk JJ.
Late pregnancy ultrasound parameters identifying fetuses at risk of adverse perinatal outcomes: a protocol for a systematic review of systematic reviews.
BMJ Open. 2022 Mar 23;12(3):e058293.

Drukker L, Droste R, Ioannou C, Impey L, Noble JA, Papageorghiou AT.
Function and Safety of SlowflowHD Ultrasound Doppler in Obstetrics.
Ultrasound Med Biol. 2022 Jun;48(6):1157-1162.

Dockree S, Shine B, Impey L, Mackillop L, Randeva H, Vatish M.
Improving diagnostic accuracy in pregnancy with individualised, gestational age-specific reference intervals.
Clin Chim Acta. 2022 Feb 15;527:56-60.

Freegard GD, Donadono V, Impey LWM.
Emergency cervical cerclage in twin and singleton pregnancies with 0-mm cervical length or prolapsed membranes.
Acta Obstet Gynecol Scand. 2021 Nov;100(11):2003-2008.

Dockree S, Shine B, Pavord S, Impey L, Vatish M.
White blood cells in pregnancy: reference intervals for before and after delivery.
EBioMedicine. 2021 Dec;74:103715

Donadono V, Manning N, Impey L.
The Antenatal and Postnatal Consequences of Antenatal Exposure to Prolonged Low Dose Indomethacin.
J Clin Med. 2021 Apr 24;10(9):1851.

Drukker L, Bradburn E, Rodriguez GB, Roberts NW, Impey L, Papageorghiou AT.
How often do we identify fetal abnormalities during routine third-trimester ultrasound? A systematic review and meta-analysis.
BJOG. 2021 Jan;128(2):259-269

Dockree S, Brook J, James T, Shine B, Impey L, Vatish M.
Pregnancy-specific reference intervals for C-reactive protein improve diagnostic accuracy for infection: A longitudinal study.
Clin Chim Acta. 2021 Jun;517:81-85.

Salim I, Staines-Urias E, Mathewlynn S, Drukker L, Vatish M, Impey L.
The impact of a routine late third trimester growth scan on the incidence, diagnosis, and management of breech presentation in Oxfordshire, UK: A cohort study.
PLoS Med. 2021 Jan 15;18(1):e1003503.

Mathewlynn S, Knutzen L, Impey L.
Intrapartum hypoxia and sexual dimorphism in adverse perinatal outcomes.
Eur J Obstet Gynecol Reprod Biol. 2020 May;248:9-13.

Drukker L, Cavallaro A, Salim I, Ioannou C, Impey L, Papageorghiou AT.
How often do we incidentally find a fetal abnormality at the routine third-trimester growth scan? A population-based study.
Am J Obstet Gynecol. 2020 Dec;223(6):919.e1-919.e13.

Edwards K, Impey L.
Extreme preterm birth in the right place: a quality improvement project.
Arch Dis Child Fetal Neonatal Ed. 2020 Jul;105(4):445-448.

Cerdeira AS, O'Sullivan J, Ohuma EO, Harrington D, Szafranski P, Black R, Mackillop L, Impey L, Greenwood et al.
Randomized Interventional Study on Prediction of Preeclampsia/Eclampsia in Women With Suspected Preeclampsia: INSPIRE.
Hypertension. 2019 Oct;74(4):983-990. doi: 10.1161/HYPERTENSIONAHA.119.12739.

The outcomes of pregnancies with reduced fetal movements: A retrospective cohort study.
Bhatia M, Mitsi V, Court L, Thampi P, El-Nasharty M, Hesham S, Randall W, Davies R, Impey L.
Acta Obstet Gynecol Scand. 2019 May 31. doi: 10.1111/aogs.13671

External cephalic version at term: a cohort study of 18 years' experience.
Melo P, Georgiou EX, Hedditch A, Ellaway P, Impey L.
BJOG. 2019 Mar;126(4):493-499.

Ruiz-Martinez S, Volpe G, Vannuccini S, Cavallaro A, Impey L, Ioannou C.
An objective scoring method to evaluate image quality of middle cerebral artery Doppler.
J Matern Fetal Neonatal Med. 2018 Jun 27:1-181.

Stevenson GN, Noble JA, Welsh AW, Impey L, Collins SL.
Automated Visualization and Quantification of Spiral Artery Blood Flow Entering the First-Trimester Placenta, Using 3-D Power Doppler Ultrasound.
Ultrasound Med Biol. 2018 Mar;44(3):522-531.

Volpe G, Ioannou C, Cavallaro A, Vannuccini S, Ruiz-Martinez S, Impey L.
The influence of fetal sex on the antenatal diagnosis of small for gestational age.
J Matern Fetal Neonatal Med. 2018 Jan 2:1-6. doi: 10.1080/14767058.2017.1419180.

Cavallaro A, Veglia M, Svirko E, Vannuccini S, Volpe G, Impey L.
Using fetal abdominal circumference growth velocity to improve the prediction of adverse outcomes in near term small for gestational age fetuses.
Ultrasound Obstet Gynecol. 2017 Dec 20. doi: 10.1002/uog.18988.

Vannuccini S, Ioannou C, Cavallaro A, Volpe G, Ruiz-Martinez S, Impey L.
A reference range of fetal abdominal circumference growth velocity between 20 and 36 weeks' gestation.
Prenat Diagn. 2017 Nov;37(11):1084-1092.

Veglia M, Cavallaro A, Papageorghiou A, Black R, Impey L.
Small for Gestational Age Babies After 37 Weeks: An Impact Study of a Risk Stratification Protocol.
Ultrasound Obstet Gynecol. 2017 Jun 10. doi: 10.1002/uog.17544

Collins SL, Welsh AW, Impey L, Noble JA, Stevenson GN.
3D fractional moving blood volume (3D-FMBV) demonstrates decreased first trimester placental vascularity in pre-eclampsia but not the term, small for gestation age baby.
PLoS One. 2017 Jun 1;12(6):e0178675.

Thakkar HS, Durell J, Chakraborty S, Tingle BL, Choi A, Fowler DJ, Gould SJ, Impey L, Lakhoo.
Antenatally Detected Congenital Pulmonary Airway Malformations: The Oxford Experience.
Eur J Pediatr Surg. 2017 Aug;27(4):324-329.

Bradshaw CJ, Thakkar H, Knutzen L, Marsh R, Pacilli M, Impey L, Lakhoo K.
Accuracy of prenatal detection of tracheoesophageal fistula and oesophageal atresia.
J Pediatr Surg. 2016 Aug;51(8):1268-72. doi: 10.1016/j.jpedsurg.2016.02.001.

Stevenson GN, Collins SL, Ding J, Impey L, Noble JA.
3-D Ultrasound Segmentation of the Placenta Using the Random Walker Algorithm: Reliability and Agreement.
Ultrasound Med Biol. 2015 Dec;41(12):3182-93. doi: 10.1016/j.ultrasmedbio.2015.07.021.

Collins SL, Stevenson GN, Al-Khan A, Illsley NP, Impey L, Pappas L, Zamudio S.
Three-Dimensional Power Doppler Ultrasonography for Diagnosing Abnormally Invasive Placenta and Quantifying the Risk.
Obstet Gynecol. 2015 Sep;126(3):645-53.

Hemelaar J, Lim LN, Impey L.
The Impact of an ECV Service is Limited by Antenatal Breech Detection: A Retrospective Cohort Study.
Birth. 2015 Jun;42(2):165-72. doi: 10.1111/birt.12162. Epub 2015 Apr 15.

Knutzen L, Svirko E, Impey L.
The significance of base deficit in acidemic term neonates.
Am J Obstet Gynecol. 2015 Sep;213(3):373.e1-7. doi: 10.1016/j.ajog.2015.03.051.

Aye CY, Stevenson GN, Impey L, Collins SL.
Comparison of 2-D and 3-D estimates of placental volume in early pregnancy.
Ultrasound Med Biol. 2015 Mar;41(3):734-40. doi: 10.1016/j.ultrasmedbio.2014.10.001. Epub 2015 Jan 22.

Thakkar HS, Bradshaw C, Impey L, Lakhoo K.
Post-natal outcomes of antenatally diagnosed intra-abdominal cysts: a 22-year single-institution series.
Pediatr Surg Int. 2015 Feb;31(2):187-90. doi: 10.1007/s00383-014-3635-2. Epub 2014 Nov 16.

Stevenson GN, Collins SL, Welsh AW, Impey L, Noble JA.
A technique for the estimation of fractional moving blood volume by using three-dimensional power Doppler US.
Radiology. 2015 Jan;274(1):230-7. doi: 10.1148/radiol.14132363. Epub 2014 Aug 12.

SL Collins, GN Stevenson, JA Noble, L Impey.
Rapid calculation of standardised placental volume at 11-13 weeks and the prediction of the term, small for gestational age baby.
Ultrasound in Medicine and Biology (2013 Feb;39(2):253-60.

S Collins, G Stevenson, A Noble, L Impey.
Developmental changes in spiral artery blood flow in the human placenta observed with colour Doppler ultrasonography
Placenta. 2012 Oct;33(10):782-7. Epub 2012 Jul 24.

P Yeh, K Emary, L Impey.
The relationship between umbilical cord arterial pH and serious adverse neonatal outcomes: analysis of 51 519 consecutive validated samples.
BJOG 2012; 119:824-831

Welsh AW, Collins SL, Stevenson GN, Noble JA, Impey L.
Inapplicability of fractional moving blood volume technique to standardize Virtual Organ Computer-aided AnaLysis indices for quantified three-dimensional power Doppler.
Ultrasound Obstet Gynecol. 2012 Dec;40(6):688-92. doi: 10.1002/uog.11139.

Collins SL, Birks JS, Stevenson GN, Papageorghiou AT, Noble JA, Impey L.
Measurement of spiral artery jets: general principles and differences observed in small-for-gestational-age pregnancies.
Ultrasound Obstet Gynecol. 2012 Aug;40(2):171-8. doi: 10.1002/uog.10149.

Collins SL, Stevenson GN, Noble JA, Impey L, Welsh AW.
Influence of power Doppler gain setting on Virtual Organ Computer-aided AnaLysis indices in vivo: can use of the individual sub-noise gain level optimize information?
Ultrasound Obstet Gynecol. 2012 Jul;40(1):75-80. doi: 10.1002/uog.10122.

M Gupta, C Hockley, M Quigley, P Yeh, L Impey.
Antepartum and intrapartum risk factors for shoulder dystocia.
European Journal of Obstetrics and Gynaecology and Reproductive Biology 2010; 151: 134-8

A Mears, J Sadiq, L Impey, K Lakhoo.
Antenatal bowel dilatation in gastroschisis: a bad sign?
Pediatr Surg Int. 2010; 26: 581-8. (epub 2010 Apr 24).

M Gupta, K Emary, L Impey
Emergency cervical cerclage: predictors of success
Journal of Maternal-Fetal and Neonatal Medicine 2010;23: 670-4

G Patel, J Sadiq, N Shenker, L Impey, K Lakhoo.
Neonatal Survival of antenatally diagnosed exomphalos
Paediatric Surgery International 2009; 25: 413-6. (epub 2009 Mar 26).

R Brettell, P Yeh, L Impey
The association between fetal gender and preterm delivery
European Journal of Obstetrics and Gynaecology and Reproductive Biology 2008; 141: 123-6

L Impey, C Greenwood, R Black, P Yeh, O Sheil, P Doyle.
The relationship between intrapartum maternal fever and acidosis as risk factors for neonatal encephalopathy
American Journal of Obstetrics and Gynecology 2008; 198: 49.e1-6.

E Svirko, J Mellanby, L Impey
The association between cord pH at birth and intellectual function in childhood
Early Human Development 2008; 84: 37-41

P Patel, J Farley, L Impey, K Lakhoo
Evaluation of a fetomaternal-surgical clinic for prenatal counselling of surgical anomalies
Pediatr Surg Int. 2008 Apr;24(4):391-4.

S Collins, P Ellaway, D Harrington, M Pandit, L Impey
The complications of external cephalic version: results from 805 consecutive attempts
BJOG 2007 114: 636-8

L Impey, M Pandit
Tocolysis for repeat external cephalic version after a failed version for breech presentation at term: a randomised double-blind placebo controlled trial’
BJOG 2005; 112: 627-31

C Greenwood, P Yudkin, S Sellers, L Impey, P Doyle
Why is there a modifying effect of gestational age on risk factors for cerebral palsy?
Archives of Disease in Childhood Fetal and Neonatal Edition 2005; 90: F141-F146

L Impey, K MacQuillan, M Reynolds, S Gates, J Murphy, O Sheil
Admission cardiotocography: a randomised controlled trial
The Lancet 2003; 361: 465-70

C Greenwood, S Lalchandani, K MacQuillan, O Sheil, J Murphy, L Impey
Meconium passed in labor: how reassuring is clear amniotic fluid?
Obstetrics and Gynecology 2003; 102: 89-93

C Greenwood, S Newman, L Impey, A Johnson
Cerebral palsy and clinical negligence litigation: a cohort study
BJOG 2003; 110: 6-11

C Greenwood, L Impey
The association of nuchal cord with cerebral palsy is influenced by recording bias
Early Human Development 2002; 68:15

L Impey, C Greenwood, K MacQuillan, M Reynolds, O Sheil
Maternal fever and neonatal encephalopathy: a prospective cohort study
British Journal of Obstetrics and Gynaecology 2001; 108: 594-7

L Impey, C Greenwood, O Sheil, K MacQuillan, M Reynolds, C Redman
The relationship between pre-eclampsia at term and neonatal encephalopathy
Archives of Diseases in Childhood, Fetal and Neonatal Edition 2001; 85: F170-2

L Impey, M Robson, K MacQuillan
Epidural analgesia need not affect operative delivery rates
American Journal of Obstetrics and Gynecology 2000; 182: 358-63

L Impey, J Hobson, C O’Herlihy
The graphic analysis of active management of labor: prospective computation of labor progress in 500 consecutive nulliparous women in spontaneous labour at term
American Journal of Obstetrics and Gynecology 2000; 183: 438-43

L Impey, D Lissoni
Outcome of external cephalic version after 36 weeks’ gestation without tocolysis
Journal of Maternal-Fetal Medicine 1999; 8: 203-7

L Impey, C O’Herlihy
First delivery after strictly defined cephalopelvic disproportion’
Obstetrics and Gynecology 1998; 92: 799-803

L Impey, J Hughes
Abdominal pain in Pregnancy: who needs to be admitted? Admissions in a district general hospital in one year.
Journal of Obstetrics and Gynaecology 1995; 15: 363-5

P Bryant, L Impey
The similarities between normal readers and developmental and acquired dyslexics
Cognition 1986; 24:12-25 (Citation classic)